Therefore you can observe lentigines or a single lentigo lesion on face, back of hands, chest and on scalp
A lentigo can grow very slowly over many years, or it can appear suddenly
Jul 17, 2017 · Noonan syndrome with multiple lentigines (NSML) is a rare genetic disorder characterized by abnormalities of the skin, the structure and function of the heart, the inner ear, the head and facial (craniofacial) area, and/or the genitals
They can be slightly scaly
The term lentigo encompasses an array of related hyperpigmented lesions, which include lentigo simplex, nevus spilus, agminated lentigines, solar lentigo, and lentigo maligna (see
There are several kinds of lentigo
Lentigines are more common among Caucasian patients, especially those with fair skin, but can occur in anyone
They are not usually accompanied by other symptoms
The lesions tend to increase in number with age, making them common among the middle age and older population
Lentigines (Age Spots, Liver Spots) Lentigines (also referred to as sun spots or liver spots) are small, flat, round spots on the skin that begin to appear later in life in sun-exposed areas
Solar lentigines are similar to freckles, but freckles tend to fade during colder months
Noonan syndrome with multiple lentigines (NSML) which is part of a group called Ras/MAPK pathway syndromes, is a rare autosomal dominant, multisystem disease caused by a mutation in the protein tyrosine phosphatase, non-receptor type 11 gene
Although they are popularly referred to as “liver spots, ” they are not caused by diseases of the liver
These irregularly-shaped darkly-colored spots can be as large as two centimeters